Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933257 | 1.00 | P2RX3 (0.39) | P2RX3P2RX2HSD17B2HSD17B1FPR2 | |
| SCHEMBL24933854 | 0.91 | FPR2 (0.37) | HSD17B2HSD17B1FPR2SCN9ATBK1 | |
| SCHEMBL24933258 | 0.88 | FPR2 (0.36) | HSD17B2HSD17B1FPR2SCN9ATBK1 | |
| SCHEMBL24933404 | 0.87 | CHRNB4 (0.46) | — | |
| SCHEMBL24933550 | 0.86 | HSD17B2 (0.37) | HSD17B2HSD17B1IRAK4 | |
| SCHEMBL24933011 | 0.86 | P2RX3 (0.39) | P2RX3P2RX2HSD17B2HSD17B1SCN9A | |
| SCHEMBL30240709 | 0.86 | HSD17B2 (0.35) | HSD17B2HSD17B1FPR2SCN9ATBK1 | |
| SCHEMBL24933826 | 0.86 | HSD17B2 (0.35) | HSD17B2HSD17B1FPR2SCN9ATBK1 | |
| SCHEMBL24933004 | 0.85 | IRAK4 (0.44) | HSD17B2HSD17B1SCN9AIRAK4 | |
| SCHEMBL24933220 | 0.85 | HSD17B2 (0.36) | HSD17B2HSD17B1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |