Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2745822 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6448524 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL2267588 | 0.77 | ALDH1A1 (0.44) | NOS1NOS2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL23043745 | 0.75 | NOS1 (0.34) | NOS1NOS2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL7500935 | 0.75 | NOS1 (0.34) | NOS1NOS2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL2392878 | 0.75 | NOS1 (0.42) | NOS1NOS2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL5608598 | 0.75 | ALDH1A1 (0.42) | NOS1NOS2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL5608594 | 0.75 | ALDH1A1 (0.42) | NOS1NOS2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL7440809 | 0.75 | ALDH1A1 (0.42) | NOS1NOS2ALDH1A1TSHR | |
| Pivalate SCHEMBL30235549 | 0.74 | ALDH1A1 (0.47) | NOS1NOS2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20080318923-A1 | 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318923-A1 | 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle | AVPR1B, AVPR1A, AVPR2 | NOS1 937/4885NOS2 635/4885ALDH1A1 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.