Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240760 | 1.00 | MAOB (0.43) | MAOBFFAR1ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL24933351 | 0.90 | MAOB (0.41) | MAOBFFAR1ADAMTS4MMP13PARP10 | |
| SCHEMBL30240693 | 0.87 | MAOB (0.41) | MAOBFFAR1ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL24933346 | 0.87 | MAOB (0.41) | MAOBFFAR1ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL30240807 | 0.86 | MAOB (0.46) | MAOBFFAR1PARP10PARP15MRGPRX4 | |
| SCHEMBL24933199 | 0.86 | MAOB (0.46) | MAOBFFAR1PARP10PARP15MRGPRX4 | |
| SCHEMBL24933615 | 0.86 | MAOB (0.60) | MAOBFFAR1ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL24932976 | 0.86 | MAOB (0.52) | MAOBCYP4F2CYP4A11PARP10PARP15 | |
| SCHEMBL24933362 | 0.86 | MAOB (0.47) | MAOBFFAR1PARP10PARP15NR4A2 | |
| SCHEMBL30240782 | 0.86 | MAOB (0.52) | MAOBCYP4F2CYP4A11PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |