Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 3/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240693 | 1.00 | MAOB (0.41) | MAOBNPC1ARHPGDRAB9A | |
| SCHEMBL24933344 | 0.88 | SIRT2 (0.48) | MAOBNPC1RAB9A | |
| SCHEMBL30240716 | 0.88 | SIRT2 (0.48) | MAOBNPC1RAB9A | |
| SCHEMBL24933661 | 0.87 | MAOB (0.42) | MAOBPARP10HSD17B1HSD17B2MRGPRX4 | |
| SCHEMBL24933457 | 0.87 | MAOB (0.43) | MAOBADAMTS4MMP13ADAMTS5PARP10 | |
| SCHEMBL30240760 | 0.87 | MAOB (0.43) | MAOBADAMTS4MMP13ADAMTS5PARP10 | |
| SCHEMBL30240807 | 0.84 | MAOB (0.46) | MAOBNPC1RAB9ASMN1; SMN2PARP10 | |
| SCHEMBL24933199 | 0.84 | MAOB (0.46) | MAOBNPC1RAB9ASMN1; SMN2PARP10 | |
| SCHEMBL24932976 | 0.84 | MAOB (0.52) | MAOBNPC1RAB9ASMN1; SMN2PARP10 | |
| SCHEMBL24933362 | 0.84 | MAOB (0.47) | MAOBPARP10FFAR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |