Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240661 | 1.00 | PARP10 (0.40) | PARP10PARP15PARP14FFAR4FFAR1 | |
| SCHEMBL24933553 | 0.85 | MAOB (0.46) | PARP10PARP15FFAR1MAOBGYS1 | |
| SCHEMBL30240692 | 0.85 | MAOB (0.46) | PARP10PARP15FFAR1MAOBGYS1 | |
| SCHEMBL24933386 | 0.84 | CDC7 (0.38) | PARP10PARP15PARP14MAOBCYP1A1 | |
| SCHEMBL30240758 | 0.83 | PARP10 (0.39) | PARP10PARP15PARP14FFAR4MAPK8 | |
| SCHEMBL24933188 | 0.83 | PARP10 (0.39) | PARP10PARP15PARP14FFAR4MAPK8 | |
| SCHEMBL30240750 | 0.83 | ALOX5AP (0.36) | FFAR4FFAR1MAOBGYS1 | |
| SCHEMBL24933807 | 0.83 | ALOX5AP (0.36) | FFAR4FFAR1MAOBGYS1 | |
| SCHEMBL24933521 | 0.83 | MAOB (0.40) | PARP10PARP15PARP14FFAR4FFAR1 | |
| SCHEMBL30240735 | 0.83 | MAOB (0.40) | PARP10PARP15PARP14FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |