Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240750 | 1.00 | ALOX5AP (0.36) | ALOX5APMAOBFFAR4FFAR1SCN9A | |
| SCHEMBL24933521 | 0.85 | MAOB (0.40) | ALOX5APMAOBFFAR4FFAR1DHODH | |
| SCHEMBL30240735 | 0.85 | MAOB (0.40) | ALOX5APMAOBFFAR4FFAR1DHODH | |
| SCHEMBL30240777 | 0.85 | PDE10A (0.39) | ALOX5APSCN9ADHODHCNR1CNR2 | |
| SCHEMBL24933803 | 0.85 | PDE10A (0.39) | ALOX5APSCN9ADHODHCNR1CNR2 | |
| SCHEMBL24933819 | 0.84 | PRKAB2 (0.40) | MAOBCNR1HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL30240770 | 0.84 | PRKAB2 (0.40) | MAOBCNR1HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL30240661 | 0.83 | PARP10 (0.40) | MAOBFFAR4FFAR1GYS1 | |
| SCHEMBL24933501 | 0.83 | PARP10 (0.40) | MAOBFFAR4FFAR1GYS1 | |
| SCHEMBL24933386 | 0.83 | CDC7 (0.38) | MAOBDHODHHSD17B1HSD17B2GYS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |