Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934157 | 0.85 | RORC (0.35) | RORCRIPK1 | |
| SCHEMBL24934049 | 0.82 | RORC (0.32) | RORC | |
| SCHEMBL24934290 | 0.73 | RORC (0.36) | RORC | |
| SCHEMBL24934038 | 0.72 | — | — | |
| SCHEMBL24933966 | 0.70 | — | — | |
| SCHEMBL24933525 | 0.70 | RORC (0.33) | RORC | |
| SCHEMBL24934159 | 0.68 | RORC (0.38) | RORC | |
| SCHEMBL24933684 | 0.67 | KIT (0.30) | RORC | |
| SCHEMBL29218162 | 0.66 | ROCK1 (0.40) | — | |
| SCHEMBL30162925 | 0.66 | ROCK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |