Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934332 | 0.85 | RORC (0.34) | RORC | |
| SCHEMBL24934038 | 0.83 | — | — | |
| SCHEMBL24934327 | 0.82 | — | — | |
| SCHEMBL24934079 | 0.82 | PYGM (0.40) | RORC | |
| SCHEMBL24934220 | 0.81 | CNR1 (0.31) | RORC | |
| SCHEMBL24934167 | 0.81 | CNR1 (0.33) | — | |
| SCHEMBL24933963 | 0.81 | MAPK10 (0.31) | — | |
| SCHEMBL24934145 | 0.78 | RORC (0.32) | RORC | |
| SCHEMBL24934259 | 0.75 | ABCG2 (0.41) | KITFLT3RORC | |
| SCHEMBL24934070 | 0.70 | GRM5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |