SCHEMBL2493359

SCHEMBL2493359

C=CC[SiH](OCCCCCCCC)OCCCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
ALDH1A1 P00352 1/20 0.36
THRB P10828 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
LPAR3 Q9UBY5 4/20 0.32
LPAR2 Q9HBW0 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
LPAR1 Q92633 2/20 0.32
CES1 P23141 1/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5055538 1.00 TSHR (0.43) TSHRALDH1A1THRBMEN1HTT
SCHEMBL7937314 0.98 TSHR (0.39) TSHRALDH1A1THRBMEN1HTT
SCHEMBL198102 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL296853 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL15090851 0.81 TSHR (0.39) TSHRALDH1A1THRBMEN1HTT
SCHEMBL22661057 0.80 TSHR (0.32) TSHR
SCHEMBL22654291 0.78 TSHR (0.46) TSHRALDH1A1PLA2G2CLPAR3LPAR2
SCHEMBL2001507 0.77
SCHEMBL22654288 0.76 TSHR (0.50) TSHRALDH1A1PLA2G2CLPAR3LPAR2
SCHEMBL2001506 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060257673-A1 Laminates, their production and use CELANESE EMULSIONS GMBH (DE) 2006-11-16 US claimed
EP-1721731-A1 Layered structure, method of its preparation and use Celanese Emulsions GmbH (DE) 2006-11-15 EP claimed
EP-4722257-A1 METHODS FOR MAKING ORGANIC-INORGANIC HYBRID DISPERSIONS WITH IMPROVED STORAGE STABILITY Celanese International Corporation (US) 2026-04-08 EP disclosed
US-9676958-B2 Polymer dispersions and their use in pigmented coating compositions CELANESE SALES GERMANY GMBH (DE) 2017-06-13 US disclosed
US-20150322279-A9 CARPET COATING COMPOSITIONS OF VINYL ACETATE HAVING IMPROVED WET AND/OR DRY STRENGTH CELANESE INT CORP (US) 2015-11-12 US disclosed
US-9175185-B2 Coating compositions having high weathering resistance, process for preparation thereof and use thereof CELANESE EMULSIONS GMBH (DE) 2015-11-03 US disclosed
US-20150247054-A1 POLYMER DISPERSIONS AND THEIR USE IN PIGMENTED COATING COMPOSITIONS CELANESE EMULSIONS GMBH (DE) 2015-09-03 US disclosed
US-20150125649-A1 CARPET COATING COMPOSITIONS OF VINYL ACETATE HAVING IMPROVED WET AND/OR DRY STRENGTH CELANESE INTERNATIONAL CORPORATION 2015-05-07 US disclosed
US-8993668-B2 Polyvinyl ester dispersions, process for preparation thereof and use thereof CELANESE EMULSIONS GMBH (DE) 2015-03-31 US disclosed
EP-2641922-B1 Aqueous binder systems and their use in producing coating compositions CELANESE EMULSIONS GMBH (DE) 2014-10-29 EP disclosed
EP-2025688-B1 Polyvinyl ester dispersions, method for their manufacture and application thereof CELANESE EMULSIONS GMBH (DE) 2014-08-20 EP disclosed
US-20050020744-A1 Coating composition and process for its preparation CELANESE EMULSIONS GMBH (DE) 2005-01-27 US disclosed
EP-1500689-A1 Coating composition and method for its preparation Celanese Emulsions GmbH (DE) 2005-01-26 EP disclosed
EP-1481028-A2 AQUEOUS COATING COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR PRODUCING, IN PARTICULAR, THIXOTROPIC COATING COMPOSITIONS Celanese Emulsions GmbH (DE) 2004-12-01 EP disclosed
EP-1370621-B1 AQUEOUS PLASTIC MATERIAL DISPERSIONS, METHOD FOR PRODUCING THE SAME AND USE THEREOF CELANESE EMULSIONS GMBH (DE) 2004-12-01 EP disclosed
US-20040077782-A1 Aqueous plastic material dispersions method for producing the same and use thereof NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2004-04-22 US disclosed
WO-2004022609-A1 METHOD FOR THE PRODUCTION OF AQUEOUS POLYMER DISPERSIONS CONTAINING VERY FEW RESIDUAL MONOMERS AND USE THEREOF CELANESE EMULSIONS GMBH (DE) 2004-03-18 WO disclosed
EP-1370621-A2 AQUEOUS PLASTIC MATERIAL DISPERSIONS, METHOD FOR PRODUCING THE SAME AND USE THEREOF Celanese Emulsions GmbH (DE) 2003-12-17 EP disclosed
WO-2003070835-A2 AQUEOUS COATING COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR PRODUCING, IN PARTICULAR, THIXOTROPIC COATING COMPOSITIONS CELANESE EMULSIONS GMBH (DE) 2003-08-28 WO disclosed
WO-2002074856-A2 AQUEOUS PLASTIC MATERIAL DISPERSIONS, METHOD FOR PRODUCING THE SAME AND USE THEREOF CLARIANT GMBH (DE) 2002-09-26 WO disclosed