SCHEMBL5055538

SCHEMBL5055538

C=CC[SiH](OCCCCCCCCCCCC)OCCCCCCCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
ALDH1A1 P00352 1/20 0.36
THRB P10828 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
LPAR3 Q9UBY5 4/20 0.32
LPAR2 Q9HBW0 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
LPAR1 Q92633 2/20 0.32
CES1 P23141 1/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2493359 1.00 TSHR (0.43) TSHRALDH1A1THRBMEN1HTT
SCHEMBL7937314 0.98 TSHR (0.39) TSHRALDH1A1THRBMEN1HTT
SCHEMBL198102 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL296853 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL15090851 0.81 TSHR (0.39) TSHRALDH1A1THRBMEN1HTT
SCHEMBL22661057 0.80 TSHR (0.32) TSHR
SCHEMBL22654291 0.78 TSHR (0.46) TSHRALDH1A1PLA2G2CLPAR3LPAR2
SCHEMBL2001507 0.77
SCHEMBL22654288 0.76 TSHR (0.50) TSHRALDH1A1PLA2G2CLPAR3LPAR2
SCHEMBL2001506 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7438860-B2 Droplet discharging head and microarray manufacturing method SEIKO EPSON CORPORATION (JP) 2008-10-21 US disclosed
US-20050008497-A1 Droplet discharging head and microarray manufacturing method SEIKO EPSON CORPORATION (JP) 2005-01-13 US disclosed