Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753067 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL7276717 | 0.92 | ALDH1A1 (0.49) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL21056638 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL31496912 | 0.86 | KDM4C (0.48) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9208694 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL6630041 | 0.81 | IDO1 (0.42) | CYP17A1KDM4CSSTR4IDO1 | |
| SCHEMBL2417380 | 0.81 | GPR119 (0.55) | KDM4EALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL30053721 | 0.81 | KDM4C (0.48) | KDM4EALDH1A1L3MBTL1KDM4CKMT2A | |
| SCHEMBL26599184 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL68952 | 0.77 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |