Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933453 | 1.00 | PARP1 (0.40) | PARP1HSD17B2HSD17B1GPR84TP53 | |
| SCHEMBL24933655 | 1.00 | PARP1 (0.40) | PARP1HSD17B2HSD17B1GPR84TP53 | |
| SCHEMBL30240749 | 0.92 | PARP1 (0.41) | PARP1HSD17B2HSD17B1TP53MAPT | |
| SCHEMBL24933022 | 0.91 | PARP1 (0.41) | PARP1HSD17B2HSD17B1TP53MAPT | |
| SCHEMBL24933041 | 0.88 | PARP1 (0.39) | PARP1HSD17B2HSD17B1TP53MAPT | |
| SCHEMBL24933744 | 0.87 | HSD17B1 (0.36) | PARP1HSD17B2HSD17B1FFAR4PRKAB2 | |
| SCHEMBL24933645 | 0.87 | HSD17B1 (0.36) | PARP1HSD17B2HSD17B1FFAR4PRKAB2 | |
| SCHEMBL24933415 | 0.87 | HSD17B1 (0.36) | PARP1HSD17B2HSD17B1FFAR4PRKAB2 | |
| SCHEMBL24933750 | 0.87 | HSD17B1 (0.36) | PARP1HSD17B2HSD17B1FFAR4PRKAB2 | |
| SCHEMBL24933551 | 0.86 | GPR84 (0.42) | PARP1HSD17B2HSD17B1GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |