Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933038 | 1.00 | PARP10 (0.34) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL31108203 | 0.97 | HSD17B1 (0.33) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL30240823 | 0.97 | HSD17B1 (0.33) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933262 | 0.97 | HSD17B1 (0.33) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933264 | 0.97 | HSD17B1 (0.33) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933891 | 0.97 | HSD17B1 (0.33) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933263 | 0.97 | HSD17B1 (0.33) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933313 | 0.88 | PRKAB2 (0.35) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933455 | 0.87 | HSD17B1 (0.35) | PARP10PARP15HSD17B1HSD17B2PRKAB2 | |
| SCHEMBL24933187 | 0.86 | HSD17B1 (0.36) | HSD17B1HSD17B2PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |