Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 5/20 | 0.38 |
| ▸ | TK1 | P04183 | 5/20 | 0.37 |
| ▸ | TK2 | O00142 | 3/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013852 | 0.81 | KIF11 (0.43) | KIF11TK1TK2DUTALDH1A1 | |
| SCHEMBL7013854 | 0.81 | KIF11 (0.43) | KIF11TK1TK2DUTALDH1A1 | |
| SCHEMBL30974560 | 0.79 | KIF11 (0.42) | KIF11TK1TK2DUTKDM4E | |
| SCHEMBL12268294 | 0.74 | DUT (0.50) | KIF11TK1TK2DUTKDM4E | |
| SCHEMBL913275 | 0.74 | DUT (0.50) | KIF11TK1TK2DUTKDM4E | |
| SCHEMBL913276 | 0.74 | DUT (0.50) | KIF11TK1TK2DUTKDM4E | |
| SCHEMBL20873778 | 0.73 | KIF11 (0.47) | KIF11TK1TK2DUTALDH1A1 | |
| SCHEMBL20873776 | 0.73 | KIF11 (0.47) | KIF11TK1TK2DUTALDH1A1 | |
| SCHEMBL6241174 | 0.71 | KIF11 (0.56) | KIF11DUTALDH1A1ALOX15 | |
| SCHEMBL28250787 | 0.71 | KIF11 (0.47) | KIF11TK1TK2DUTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373809-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | Novartis AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |