Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240711 | 1.00 | SYK (0.42) | SYKHSD17B1HSD17B2DHODHPARP10 | |
| SCHEMBL30240779 | 0.87 | PARP10 (0.51) | SYKDHODHPARP10MAPK14SMO | |
| SCHEMBL24933620 | 0.87 | PARP10 (0.51) | SYKDHODHPARP10MAPK14SMO | |
| SCHEMBL24933881 | 0.87 | HSD17B1 (0.38) | HSD17B1HSD17B2DHODHMAPK14SMO | |
| SCHEMBL24933841 | 0.87 | HDAC1 (0.36) | HSD17B1HSD17B2DHODHPRKAB2PRKAG1 | |
| SCHEMBL24933386 | 0.87 | CDC7 (0.38) | HSD17B1HSD17B2DHODHPARP10CDK5 | |
| SCHEMBL24933845 | 0.86 | SYK (0.42) | SYKHSD17B1HSD17B2DHODHPARP10 | |
| SCHEMBL24933808 | 0.86 | PDE10A (0.39) | HSD17B1HSD17B2DHODHPARP10PRKAB2 | |
| SCHEMBL24933190 | 0.86 | PRKAB2 (0.48) | DHODHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL24933646 | 0.85 | MAOB (0.44) | HSD17B1HSD17B2DHODHPARP10CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |