Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240673 | 1.00 | PARP10 (0.39) | PARP10PARP15PARP14MAOBHSD17B1 | |
| SCHEMBL24933639 | 0.89 | NMT1 (0.40) | PARP10PARP15PARP14MAOBHSD17B1 | |
| SCHEMBL30240735 | 0.88 | MAOB (0.40) | PARP10PARP15PARP14MAOBHSD17B1 | |
| SCHEMBL24933521 | 0.88 | MAOB (0.40) | PARP10PARP15PARP14MAOBHSD17B1 | |
| SCHEMBL24933641 | 0.87 | MAOB (0.39) | PARP10PARP15PARP14MAOBHSD17B1 | |
| SCHEMBL30240668 | 0.87 | MAOB (0.39) | PARP10PARP15PARP14MAOBHSD17B1 | |
| SCHEMBL24933222 | 0.85 | PRKAB2 (0.44) | PARP10MAOBHSD17B1HSD17B2PARP1 | |
| SCHEMBL29203327 | 0.83 | ALK (0.38) | HSD17B1HSD17B2GPBAR1CDC7SCN9A | |
| SCHEMBL24933028 | 0.83 | PARP10 (0.41) | PARP10PARP15PARP14HSD17B1HSD17B2 | |
| SCHEMBL30240731 | 0.83 | PARP10 (0.41) | PARP10PARP15PARP14HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |