Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099559 | 0.85 | SMN1; SMN2 (0.76) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL18232439 | 0.85 | RAB9A (0.76) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL18769014 | 0.85 | RAB9A (0.55) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL104476 | 0.85 | SMN1; SMN2 (0.76) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10099556 | 0.84 | RAB9A (0.75) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL104431 | 0.84 | RAB9A (0.75) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL5049348 | 0.82 | RAB9A (0.72) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL23903366 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL18232443 | 0.82 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL15982295 | 0.80 | CA2 (0.78) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |