SCHEMBL24934780

SCHEMBL24934780

CC(C)C(=O)COCCCCOc1c(F)cc(C(C)C)cc1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.36
EIF4A3 P38919 1/20 0.34
KDM4E B2RXH2 3/20 0.34
FFAR1 O14842 2/20 0.33
RXRA P19793 3/20 0.32
PPARG P37231 3/20 0.32
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CASP3 P42574 1/20 0.31
RARG P13631 2/20 0.31
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
CTSH P09668 2/20 0.30
CTSK P43235 2/20 0.30
CTSV O60911 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24935559 0.99 FFAR4 (0.35) FFAR4EIF4A3KDM4EFFAR1RXRA
SCHEMBL24934777 0.87 CCNT1 (0.37) FFAR4KDM4EFFAR1ALDH1A1CASP3
SCHEMBL25063752 0.83 EIF4A3 (0.31) EIF4A3RXRAPPARGRARG
SCHEMBL25063933 0.82 MRGPRX4 (0.40) KDM4EFFAR1ALDH1A1LMNA
SCHEMBL25063758 0.81 EIF4A3 (0.33) FFAR4EIF4A3FFAR1RXRAPPARG
SCHEMBL24934759 0.80 FFAR1 (0.40) KDM4EFFAR1PPARG
SCHEMBL25063930 0.80 EIF4A3 (0.38) FFAR4EIF4A3KDM4EFFAR1RXRA
SCHEMBL25063857 0.77 ACKR3 (0.34) KDM4ERARARARBALDH1A1LMNA
SCHEMBL24935185 0.75 KMT2A (0.50) KDM4ERXRARXRB
SCHEMBL25063926 0.75 KDM4E (0.42) KDM4EFFAR1ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230054270-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) 2023-02-23 US disclosed
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230054270-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AR, SHBG, NR5A1 FFAR4 823/4885EIF4A3 3940/4885KDM4E 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.