SCHEMBL24935559

SCHEMBL24935559

CC(C)C(=O)COCCCCCOc1c(F)cc(C(C)C)cc1F

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.35
KDM4E B2RXH2 2/20 0.33
EIF4A3 P38919 1/20 0.33
FFAR1 O14842 4/20 0.33
CES2 O00748 2/20 0.32
RXRA P19793 3/20 0.32
PPARG P37231 3/20 0.32
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
CASP3 P42574 1/20 0.31
RARG P13631 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24934780 0.99 FFAR4 (0.36) FFAR4KDM4EEIF4A3FFAR1RXRA
SCHEMBL24934777 0.86 CCNT1 (0.37) FFAR4KDM4EFFAR1ALDH1A1CASP3
SCHEMBL25063933 0.83 MRGPRX4 (0.40) KDM4EFFAR1ALDH1A1LMNATHRA
SCHEMBL25063752 0.82 EIF4A3 (0.31) EIF4A3RXRAPPARGRARG
SCHEMBL25063758 0.80 EIF4A3 (0.33) FFAR4EIF4A3FFAR1RXRAPPARG
SCHEMBL24934759 0.79 FFAR1 (0.40) KDM4EFFAR1PPARGTHRATHRB
SCHEMBL25063930 0.79 EIF4A3 (0.38) FFAR4KDM4EEIF4A3FFAR1CES2
SCHEMBL20225814 0.76 THRA (0.39) RXRAPPARGRARARARBRXRB
SCHEMBL25063857 0.76 ACKR3 (0.34) KDM4ERARARARBALDH1A1LMNA
SCHEMBL21778813 0.75 FABP3 (0.35) FFAR4KDM4EEIF4A3FFAR1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed