Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542117 | 0.93 | SMN1; SMN2 (0.83) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL24819419 | 0.90 | SMN1; SMN2 (0.73) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL24935013 | 0.87 | MEN1 (0.71) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL2456637 | 0.86 | SMN1; SMN2 (0.73) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL10746702 | 0.85 | MEN1 (0.71) | SMN1; SMN2GAARAB9APOLBMEN1 | |
| SCHEMBL22758337 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL17183464 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL257816 | 0.84 | EPHX2 (0.76) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL9312345 | 0.84 | EPHX2 (0.76) | SMN1; SMN2GAARAB9APOLBEPHX2 | |
| SCHEMBL24935402 | 0.83 | NPC1 (0.71) | SMN1; SMN2GAARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |