Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685426 | 0.87 | NR1H4 (0.73) | NPC1RAB9ASMN1; SMN2MAPTNR1H4 | |
| SCHEMBL24935348 | 0.84 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTNR1H4 | |
| SCHEMBL5438741 | 0.84 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2MAPTNR1H4 | |
| SCHEMBL822378 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27181403 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL12310125 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL14580374 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL15214321 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL24935012 | 0.83 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8361567 | 0.83 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MAPTCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |