Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542117 | 0.90 | SMN1; SMN2 (0.83) | MEN1KMT2ASMN1; SMN2GAARAB9A | |
| SCHEMBL24819419 | 0.87 | SMN1; SMN2 (0.73) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24935012 | 0.87 | SMN1; SMN2 (0.73) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10201372 | 0.85 | RAB9A (0.72) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2456637 | 0.83 | SMN1; SMN2 (0.73) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24935017 | 0.83 | SMN1; SMN2 (0.64) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10746702 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22758337 | 0.82 | SMN1; SMN2 (0.71) | MEN1KMT2ASMN1; SMN2GAARAB9A | |
| SCHEMBL17183464 | 0.82 | SMN1; SMN2 (1.00) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9312345 | 0.81 | EPHX2 (0.76) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |