SCHEMBL24935554

SCHEMBL24935554

CC(=O)COCC(F)CCOc1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
LMNA P02545 2/20 0.41
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.41
NPC1 O15118 2/20 0.40
HPGD P15428 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK1 P28482 1/20 0.39
MAPT P10636 1/20 0.39
PTGES O14684 1/20 0.39
ALOX5 P09917 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24935694 0.81 L3MBTL1 (0.42) MEN1KMT2AL3MBTL1LMNAGAA
SCHEMBL24935659 0.81 MRGPRX4 (0.44) L3MBTL1LMNAALDH1A1MAPT
SCHEMBL24935608 0.80 PPARG (0.36) L3MBTL1ATMHPGDALDH1A1TDP1
SCHEMBL19599651 0.79 L3MBTL1 (0.56) MEN1KMT2AL3MBTL1LMNAGAA
SCHEMBL24935555 0.77 L3MBTL1 (0.54) MEN1KMT2AL3MBTL1GAANPC1
SCHEMBL18495410 0.75 L3MBTL1 (0.51) MEN1KMT2AL3MBTL1LMNAGAA
SCHEMBL17174025 0.75 L3MBTL1 (0.51) MEN1KMT2AL3MBTL1LMNAGAA
SCHEMBL25063891 0.75 RAB9A (0.41) MEN1KMT2AGAANPC1ALDH1A1
SCHEMBL8234368 0.73 MAPT (0.59) MEN1KMT2AL3MBTL1LMNAGAA
SCHEMBL24934755 0.73 MRGPRX4 (0.41) L3MBTL1LMNAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed