Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13599210 | 0.97 | NAMPT (0.47) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL26700954 | 0.97 | NAMPT (0.47) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL26700952 | 0.97 | NAMPT (0.47) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL23729307 | 0.97 | NAMPT (0.47) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL16248541 | 0.97 | NAMPT (0.47) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL21029751 | 0.95 | NAMPT (0.45) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL26700957 | 0.95 | NAMPT (0.45) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL16843241 | 0.93 | CASP2 (0.44) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL26818739 | 0.92 | LMNA (0.44) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL18768810 | 0.91 | CASP2 (0.52) | CASP2FAAHNAAAALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |