Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 6/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | PI4KA | P42356 | 3/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857280 | 0.92 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL24936176 | 0.76 | TBXAS1 (0.37) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL27045780 | 0.76 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL2262566 | 0.74 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL27045457 | 0.72 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL18250320 | 0.72 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL2262558 | 0.71 | IDO1 (0.43) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL18250245 | 0.70 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL22939918 | 0.69 | IDO1 (0.42) | HSP90AA1HSP90AB1IDO1PIM1MARK3 | |
| SCHEMBL22940945 | 0.69 | IDO1 (0.42) | HSP90AA1HSP90AB1IDO1PIM1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | MYC, WDR5, MYCBP | HSP90AA1 1825/4885HSP90AB1 1688/4885IDO1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.