Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 4/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494485 | 0.96 | CHRM1 (0.37) | CHRM1CLK1RAB9AEGFRHPGD | |
| SCHEMBL2492610 | 0.89 | CHRM1 (0.40) | CHRM1CLK1RAB9AHPGDMEN1 | |
| SCHEMBL2495645 | 0.88 | CHRM1 (0.41) | CHRM1CLK1RAB9AMETCNR1 | |
| SCHEMBL2584680 | 0.86 | CHRM1 (0.37) | CHRM1CLK1RAB9AMETCNR1 | |
| SCHEMBL2495082 | 0.84 | CHRM1 (0.40) | CHRM1CLK1RAB9AMETCNR1 | |
| SCHEMBL7910850 | 0.83 | CHRM1 (0.35) | CHRM1CLK1RAB9AHTR1AHTR7 | |
| SCHEMBL2586715 | 0.83 | CHRM1 (0.37) | CHRM1CLK1RAB9AEGFRHPGD | |
| Hydrochloric Acid SCHEMBL2488605 | 0.83 | CHRM1 (0.34) | CHRM1CLK1RAB9AHTR1AHTR7 | |
| SCHEMBL2458294 | 0.82 | CHRM1 (0.43) | CHRM1CLK1RAB9AHPGDMEN1 | |
| SCHEMBL2578253 | 0.82 | CHRM1 (0.40) | CHRM1CLK1RAB9AFAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |