SCHEMBL2586715

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2584779	0.93	CHRM1 (0.39)	CHRM1CLK1RAB9AHPGDCNR1
	SCHEMBL2489724	0.89	MAPT (0.37)	CHRM1HPGDKEAP1NFE2L2MAOB
	SCHEMBL2490834	0.89	CHRM1 (0.36)	CHRM1CLK1RAB9ACNR1CNR2
	SCHEMBL2535340	0.87	CHRM1 (0.34)	CHRM1CLK1RAB9ACNR1CNR2
	SCHEMBL2494485	0.86	CHRM1 (0.37)	CHRM1CLK1RAB9AHPGDEGFR
	SCHEMBL15474182	0.86	CHRM1 (0.35)	CHRM1CLK1RAB9ACNR1CNR2
	SCHEMBL7900961	0.85	HTR1A (0.40)	HPGD
	SCHEMBL2458294	0.85	CHRM1 (0.43)	CHRM1CLK1RAB9AHPGDKEAP1
	Hydrochloric Acid SCHEMBL2492090	0.84	HTR1A (0.40)	RAB9AHPGD
	SCHEMBL2463173	0.83	CHRM1 (0.42)	CHRM1CLK1RAB9AHPGDHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.