Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fenoterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 20/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | ADRB3 | P13945 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | MC4R | P32245 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | MC3R | P41968 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenoterol SCHEMBL9971022 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL9971023 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL5009 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL9971031 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL28315409 | 0.98 | ADRB2 (0.97) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL29378231 | 0.98 | ADRB2 (0.97) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL1604836 | 0.98 | ADRB2 (0.97) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL121549 | 0.98 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL4307761 | 0.97 | ADRB2 (0.94) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL15517852 | 0.96 | ADRB2 (0.92) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4659160-B2 | — | — | 2011-03-30 | — | — | JP | claimed |
| EP-1338528-B1 | Use of a container for medical liquid | BOEHRINGER INGELHEIM INT (DE) | 2008-03-12 | — | — | EP | claimed |
| EP-1214985-B1 | Device of miniaturised construction for producing high pressure in a fluid to be atomised | BOEHRINGER INGELHEIM INT (DE) | 2007-01-24 | — | — | EP | claimed |
| US-20060285987-A1 | Device for Producing High Pressure in a Fluid in Miniature | JAEGER JOACHIM | 2006-12-21 | — | — | US | claimed |
| US-7104470-B2 | Device for producing high pressure in a fluid in miniature | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-09-12 | — | — | US | claimed |
| US-6988496-B1 | Cartridge for a liquid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-24 | — | — | US | claimed |
| US-20050252990-A1 | Device for producing high pressure in a fluid in miniature | JAEGER JOACHIM | 2005-11-17 | — | — | US | claimed |
| EP-1156769-B1 | CARTRIDGE FOR A LIQUID | BOEHRINGER INGELHEIM INT (DE) | 2004-09-29 | — | — | EP | claimed |
| US-20040178227-A1 | Device for producing high pressure in a fluid in miniature | BOEHRINGER INTERNATIONAL GMBH (DE) | 2004-09-16 | — | — | US | claimed |
| US-20040143235-A1 | Container for a medicinal liquid | BOEHRINGER INGELHEIM GMBH | 2004-07-22 | — | — | US | claimed |
| EP-1156769-A2 | CARTRIDGE FOR A LIQUID | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 2001-11-28 | — | — | EP | claimed |
| US-20010008632-A1 | AQUEOUS MEDICAMENT PREPARATIONS FOR THE PRODUCTION OF PROPELLENT GAS-FREE AEROSOLS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-19 | — | — | US | claimed |
| EP-1058657-A1 | CONTAINER FOR A MEDICINAL LIQUID | Boehringer Ingelheim International GmbH (DE) | 2000-12-13 | — | — | EP | claimed |
| WO-2000049988-A2 | CARTRIDGE FOR A LIQUID | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2000-08-31 | — | — | WO | claimed |
| CN-1240347-A | New aqueous medicament preparations for the production of propellent gas-free aerosols | BOEHRINGER INGELHELM KG (DE) | 2000-01-05 | — | — | CN | claimed |
| EP-0946146-A2 | NEW AQUEOUS MEDICAMENT PREPARATIONS FOR THE PRODUCTION OF PROPELLENT GAS-FREE AEROSOLS | Boehringer Ingelheim Pharma KG (DE) | 1999-10-06 | — | — | EP | claimed |
| WO-1999043571-A1 | CONTAINER FOR A MEDICINAL LIQUID | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 1999-09-02 | — | — | WO | claimed |
| EP-0853501-A1 | DEVICE OF MINIATURISED CONSTRUCTION FOR PRODUCING HIGH PRESSURE IN A FLUID TO BE ATOMISED | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1998-07-22 | — | — | EP | claimed |
| WO-1998027959-A2 | NEW AQUEOUS MEDICAMENT PREPARATIONS FOR THE PRODUCTION OF PROPELLENT GAS-FREE AEROSOLS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-07-02 | — | — | WO | claimed |
| WO-1997012687-A1 | DEVICE OF MINIATURISED CONSTRUCTION FOR PRODUCING HIGH PRESSURE IN A FLUID TO BE ATOMISED | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 1997-04-10 | — | — | WO | claimed |