Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fenoterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 20/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | ADRB3 | P13945 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | MC4R | P32245 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | MC3R | P41968 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenoterol SCHEMBL9971022 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL9971023 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL249376 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL9971031 | 1.00 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL28315409 | 0.98 | ADRB2 (0.97) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL29378231 | 0.98 | ADRB2 (0.97) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL1604836 | 0.98 | ADRB2 (0.97) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL121549 | 0.98 | ADRB2 (1.00) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL4307761 | 0.97 | ADRB2 (0.94) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 | |
| Fenoterol SCHEMBL15517852 | 0.96 | ADRB2 (0.92) | ADRB2CYP3A4MAPK1NPSR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 24811 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423298-B1 | — | — | None | — | — | US | claimed |
| US-20260132115-A1 | SUBSTITUTED 3-FLUOROBENZENEPROPANOATE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | TIANJIN GUDUI BIO PHARM CO LTD (CN) | 2026-05-14 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| EP-4434588-B1 | AEROSOL DELIVERY DEVICE | PARI PHARMA GMBH (DE) | 2026-04-08 | — | — | EP | claimed |
| CN-121586705-A | Small molecule prostaglandin F receptor antagonists | 辉凌公司 | 2026-02-27 | — | — | CN | claimed |
| US-12545948-B2 | Identification of novel loci in asthma and methods of use thereof for the diagnosis and treatment of asthma | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2026-02-10 | — | — | US | claimed |
| US-20260021124-A1 | BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | GENETIC S P A (IT) | 2026-01-22 | — | — | US | claimed |
| US-12453727-B2 | Montelukast salts and pharmaceutical compositions containing the same | GENETIC S.P.A. (IT) | 2025-10-28 | — | — | US | claimed |
| US-20250312274-A1 | A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-10-09 | — | — | US | claimed |
| WO-1987005213-A1 | NEW PHARMACEUTICAL COMPOSITIONS FOR INHALATION | CHIESI FARMACEUTICI S.P.A. (IT) | 1987-09-11 | — | — | WO | claimed |
| EP-0036426-B1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES | INTERx RESEARCH CORPORATION (US) | 1986-04-23 | — | — | EP | claimed |
| EP-0085514-A2 | Compositions comprising a beta-antagonist and a beta-agonist, their preparation, and their use in treating obese humans and animals | BEECHAM GROUP PLC (GB) | 1983-08-10 | — | — | EP | claimed |
| US-4386062-A | Intradermal horse sweat test | RESEARCH CORPORATION (US) | 1983-05-31 | — | — | US | claimed |
| US-4385048-A | Methods for the treatment of nasal hypersecretion | BOEHRINGER INGELHEIM GMBH (DE) | 1983-05-24 | — | — | US | claimed |
| EP-0036426-A4 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. | INTERX RESEARCH CORP (US) | 1983-03-29 | — | — | EP | claimed |
| US-4313956-A | Novel sypathomimetic amine prodrugs | INTERX RESEARCH CORP. (US) | 1982-02-02 | — | — | US | claimed |
| EP-0036426-A1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. | INTERX RESEARCH CORP (US) | 1981-09-30 | — | — | EP | claimed |
| US-4275219-A | Novel process and intermediates useful in the preparation of sympathomimetic amines | INTERX RESEARCH CORPORATION (US) | 1981-06-23 | — | — | US | claimed |
| WO-1981000849-A1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES | INTERX RESEARCH CORP (US) | 1981-04-02 | — | — | WO | claimed |