Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24937731 | 0.91 | NOTUM (0.58) | SMN1; SMN2NOTUMPOLBSIGMAR1ALDH1A1 | |
| SCHEMBL4019697 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT | |
| SCHEMBL24937798 | 0.79 | NOTUM (0.61) | SMN1; SMN2NOTUMPOLBHSD17B10SIGMAR1 | |
| SCHEMBL1855923 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2NOTUMPOLBHSD17B10SIGMAR1 | |
| SCHEMBL2829456 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT | |
| SCHEMBL4291340 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT | |
| SCHEMBL29353444 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT | |
| SCHEMBL330273 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT | |
| Hydrochloric Acid SCHEMBL11845665 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT | |
| SCHEMBL771590 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2NOTUMPOLBSIGMAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | THE UNIVERSITY OF TOKYO (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | UTS2R, TAS1R1, ULK3 | SMN1; SMN2 4875/4885NOTUM 1450/4885POLB 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.