SCHEMBL24937741

SCHEMBL24937741

O=C(N1CCN(c2ccc([N+](=O)[O-])c3nonc23)CC1)n1nccn1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.62
KMT2A Q03164 6/20 0.62
POLB P06746 3/20 0.62
USP2 O75604 3/20 0.62
TNNI3 P19429 2/20 0.62
TNNT2 P45379 2/20 0.62
TNNC1 P63316 2/20 0.62
OPRK1 P41145 1/20 0.51
MAPT P10636 9/20 0.48
ALDH1A1 P00352 3/20 0.48
S100A4 P26447 2/20 0.48
HTT P42858 2/20 0.48
THRB P10828 2/20 0.48
RECQL P46063 1/20 0.48
RAB9A P51151 2/20 0.43
MTOR P42345 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NAMPT P43490 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24937746 0.84 MEN1 (0.59) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL5301047 0.83 MEN1 (0.68) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL3500025 0.79 MEN1 (0.97) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL5244073 0.79 MEN1 (0.61) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL6391113 0.78 MEN1 (0.75) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL3505138 0.78 MEN1 (1.00) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL8159616 0.77 KMT2A (0.70) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL5242737 0.77 MEN1 (0.70) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL3502339 0.76 MEN1 (0.77) MEN1KMT2APOLBUSP2TNNI3
SCHEMBL5341701 0.76 MEN1 (0.68) MEN1KMT2APOLBUSP2TNNI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024778-A1 STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND THE UNIVERSITY OF TOKYO (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024778-A1 STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND UTS2R, TAS1R1, ULK3 MEN1 4204/4885KMT2A 3299/4885POLB 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.