Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20290478 | 0.91 | STAT3 (0.51) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL24937918 | 0.91 | STAT3 (0.51) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL18492637 | 0.90 | CRBN (0.51) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL24458964 | 0.85 | HDAC1 (0.48) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL18493738 | 0.84 | CRBN (0.66) | CRBNDDB1BRD4 | |
| SCHEMBL24391012 | 0.83 | CRBN (0.47) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL20327281 | 0.80 | STAT3 (0.46) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL24391115 | 0.80 | CRBN (0.45) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL24391114 | 0.80 | CRBN (0.45) | STAT3CRBNDDB1HDAC1HDAC6 | |
| SCHEMBL24391002 | 0.79 | CRBN (0.67) | STAT3CRBNDDB1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119552-A1 | REGULATING CHIMERIC ANTIGEN RECEPTORS | Dana-Farber Cancer Institute, Inc. (US) | 2023-01-18 | — | — | EP | disclosed |