Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 3/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458964 | 0.90 | HDAC1 (0.48) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL20290478 | 0.89 | STAT3 (0.51) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL20327713 | 0.85 | CRBN (0.68) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL20291175 | 0.85 | CRBN (0.68) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL22276598 | 0.84 | CRBN (0.52) | CRBNDDB1HDAC1HDAC3BRD4 | |
| SCHEMBL24937926 | 0.83 | STAT3 (0.50) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL20291174 | 0.83 | CRBN (0.58) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL24937918 | 0.82 | STAT3 (0.51) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL24391115 | 0.81 | CRBN (0.45) | CRBNDDB1HDAC1HDAC6HDAC3 | |
| SCHEMBL24391004 | 0.81 | CRBN (0.71) | CRBNDDB1HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135967-A1 | TUNABLE ENDOGENOUS PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135967-A1 | TUNABLE ENDOGENOUS PROTEIN DEGRADATION | PSMG3, MYCBP, DBN1 | CRBN 138/4885DDB1 26/4885HDAC1 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.