Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824110 | 0.88 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL13256587 | 0.86 | SMN1; SMN2 (0.62) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL516998 | 0.85 | LMNA (0.72) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL11985689 | 0.84 | MAPT (0.73) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL20073174 | 0.83 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL12532606 | 0.83 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL1925920 | 0.82 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL18668887 | 0.82 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL1987834 | 0.82 | TSHR (0.68) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL22283522 | 0.82 | NPC1 (0.51) | MAPTSMN1; SMN2NPC1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119539-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2023-01-18 | — | — | EP | disclosed |