Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143910 | 0.84 | KDM4E (0.48) | KDM4ETHRBRECQLMAPTALOX15 | |
| SCHEMBL9614381 | 0.81 | KDM4E (0.46) | KDM4ETHRBRECQLMAPTALOX15 | |
| SCHEMBL10066466 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TGFBR1 | |
| SCHEMBL3869217 | 0.79 | KDM4E (0.44) | KDM4ETHRBRECQLMAPTALOX15 | |
| SCHEMBL9336407 | 0.79 | KDM4E (0.44) | KDM4ETHRBRECQLMAPTALOX15 | |
| SCHEMBL8986556 | 0.77 | — | — | |
| SCHEMBL8986552 | 0.77 | — | — | |
| SCHEMBL2165150 | 0.75 | ALOX15 (0.41) | KDM4ETHRBRECQLMAPTALOX15 | |
| Butane SCHEMBL5183779 | 0.75 | KDM4E (0.46) | KDM4ETHRBRECQLMAPTALOX15 | |
| SCHEMBL14274016 | 0.74 | POLB (0.34) | MAPTTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119539-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2023-01-18 | — | — | EP | disclosed |