SCHEMBL2493952

SCHEMBL2493952

Nc1n[nH]c(-c2nc(N)n[nH]2)n1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 4/20 0.58
CYP1A2 P05177 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
ALPL P05186 1/20 0.54
HSD17B10 Q99714 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 2/20 0.45
GAA P10253 2/20 0.45
POLB P06746 1/20 0.45
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
TP53 P04637 2/20 0.42
MAPT P10636 2/20 0.40
LMNA P02545 2/20 0.40
AOC3 Q16853 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11341906 0.75 ALDH1A1 (0.59) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL2847578 0.75 KDM4E (1.00) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL8726601 0.75 ALPL (0.71) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL4607720 0.74 KDM4E (0.68) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL18278940 0.74 KDM4E (0.57) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL18284665 0.72 ALDH1A1 (0.56) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL8731546 0.72 KDM4E (0.92) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL7819474 0.72 ALPL (1.00) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL18278863 0.72 HSD17B10 (0.56) KDM4EALDH1A1CYP1A2MEN1KMT2A
SCHEMBL21359662 0.72 ALPL (0.67) KDM4EALDH1A1CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9481656-B2 3,3′-dinitro-5,5′-bis-triazole-1,1′-diol LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2016-11-01 US claimed
US-20160024029-A1 3,3'-DINITRO-5,5'-BISTRIAZOLE-1'-DIOL LUDWIG MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2016-01-28 US claimed
US-9481656-B2 3,3′-dinitro-5,5′-bis-triazole-1,1′-diol LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2016-11-01 US disclosed
US-20160024029-A1 3,3'-DINITRO-5,5'-BISTRIAZOLE-1'-DIOL LUDWIG MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2016-01-28 US disclosed
EP-2925733-A1 3,3'-DINITRO-5,5'-BISTRIAZOLE-1,1'-DIOL Ludwig-Maximilians-Universität München (DE) 2015-10-07 EP disclosed
WO-2014086599-A1 3,3'-DINITRO-5,5'-BISTRIAZOLE-1,1'-DIOL LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2014-06-12 WO disclosed
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
EP-2380208-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed