Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666683 | 0.86 | MAPT (0.54) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL8347036 | 0.84 | ALOX15 (0.64) | MAPTGAAGSK3BALOX15CES2 | |
| SCHEMBL29629345 | 0.84 | ALOX15 (0.64) | MAPTGAAGSK3BALOX15CES2 | |
| SCHEMBL1429602 | 0.82 | MAPT (0.51) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL30863507 | 0.82 | HSP90AB1 (0.67) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL29922078 | 0.82 | MAPT (0.51) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL28566027 | 0.82 | LMNA (0.51) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL7534898 | 0.82 | HSP90AB1 (0.67) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL31105825 | 0.82 | HSP90AB1 (0.66) | MAPTLMNANPC1GAAALOX12 | |
| SCHEMBL3844607 | 0.82 | HSP90AB1 (0.66) | MAPTLMNANPC1GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023001028-A1 | HETEROARYL-3-PIPERIDINEDIONE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |