SCHEMBL24939668

SCHEMBL24939668

O=C(O)c1ccc(N2C(=O)C3=C(CCCC3)C2=O)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 1/20 0.44
HIPK4 Q8NE63 1/20 0.44
SCN2A Q99250 1/20 0.44
TYMS P04818 1/20 0.40
CTDSP1 Q9GZU7 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RXFP1 Q9HBX9 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24939830 0.84 PIM3 (0.64) PIM3HIPK4SCN2ATYMSMEN1
SCHEMBL24938791 0.82 TYMS (0.49) PIM3HIPK4SCN2ATYMSMEN1
SCHEMBL24939771 0.82 PIM3 (0.44) PIM3HIPK4SCN2ATYMS
SCHEMBL24939816 0.82 PIM3 (0.44) PIM3HIPK4SCN2ATYMSCTDSP1
SCHEMBL26679375 0.81 CA12 (0.54) PIM3HIPK4SCN2APTGS1PTGS2
SCHEMBL9309327 0.81 PIM3 (0.49) PIM3HIPK4SCN2ATYMSPTGS2
SCHEMBL24939784 0.80 PIM3 (0.43) PIM3HIPK4SCN2ATYMS
SCHEMBL8560334 0.79 TDP1 (0.50) PIM3HIPK4SCN2ACTDSP1CA12
SCHEMBL24939829 0.79 ALDH1A1 (0.47) PIM3HIPK4SCN2ATYMSPTGS1
SCHEMBL9736622 0.78 ALDH1A1 (0.41) TYMSSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA PIM3 1314/4885HIPK4 519/4885SCN2A 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.