SCHEMBL8560334

SCHEMBL8560334

O=C(O)c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
CTSB P07858 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
POLB P06746 2/20 0.48
CASP6 P55212 2/20 0.48
CTDSP1 Q9GZU7 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 4/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TP53 P04637 1/20 0.45
PPOX P50336 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
TSHR P16473 1/20 0.43
NSD2 O96028 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765179 0.87 PPOX (0.43) TDP1CTSBALDH1A1LMNAMAPT
SCHEMBL9737247 0.87 ALDH1A1 (0.62) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL9309327 0.84 PIM3 (0.49) TDP1CTSBKDM4EALDH1A1HPGD
SCHEMBL11060009 0.83 MEN1 (0.58) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL24939830 0.81 PIM3 (0.64) CTSBPOLBKDM4EALDH1A1MAPT
SCHEMBL6916218 0.80 ALDH1A1 (0.37) TDP1CTSBL3MBTL1POLBCASP6
SCHEMBL7711735 0.80 PPOX (0.47) MAPTPPOXPIM3HIPK4SCN2A
SCHEMBL24939816 0.79 PIM3 (0.44) TDP1L3MBTL1POLBCASP6CTDSP1
SCHEMBL24939668 0.79 PIM3 (0.44) TDP1L3MBTL1POLBCASP6CTDSP1
SCHEMBL24939771 0.79 PIM3 (0.44) PIM3HIPK4SCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548593-B1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient MITSUBISHI CHEM CORP (JP) 1998-04-22 EP disclosed
US-5405828-A Selective pre- and postemergence herbicides MITSUBISHI KASEI CORPORATION (JP) 1995-04-11 US disclosed
US-5324709-A Safety on crops MITSUBISHI KASEI CORPORATION (JP) 1994-06-28 US disclosed
EP-0548593-A1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient Mitsubishi Chemical Corporation (JP) 1993-06-30 EP disclosed