Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.41 |
| ▸ | AXL | P30530 | 5/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187362 | 1.00 | TTK (0.41) | TTKAXLPTK6 | |
| SCHEMBL22123713 | 0.96 | TTK (0.43) | TTKAXL | |
| SCHEMBL22139188 | 0.96 | TTK (0.43) | TTKAXL | |
| SCHEMBL24940098 | 0.96 | TTK (0.43) | TTKAXL | |
| SCHEMBL22139156 | 0.95 | TTK (0.39) | TTKAXLPTK6 | |
| SCHEMBL22154431 | 0.95 | TTK (0.39) | TTKAXLPTK6 | |
| SCHEMBL22123281 | 0.95 | TTK (0.39) | TTKAXLPTK6 | |
| SCHEMBL24940127 | 0.92 | TTK (0.47) | TTKAXL | |
| SCHEMBL30187415 | 0.92 | TTK (0.47) | TTKAXL | |
| SCHEMBL24112106 | 0.91 | TTK (0.44) | TTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | claimed |
| US-20230013602-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230013602-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | IL4, RPS4Y1, RPS4X | TTK 4519/4885AXL 2653/4885PTK6 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.