Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24940688 | 0.91 | FFAR1 (0.36) | — | |
| SCHEMBL24940635 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL24940639 | 0.85 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL24939927 | 0.83 | FFAR1 (0.35) | RARBRARARARG | |
| SCHEMBL24940677 | 0.83 | FFAR1 (0.37) | — | |
| SCHEMBL24939900 | 0.82 | TSHR (0.39) | RARBRARARARG | |
| SCHEMBL24940758 | 0.82 | TSHR (0.39) | RARBRARARARG | |
| SCHEMBL24940695 | 0.82 | FFAR1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL24940763 | 0.81 | FFAR1 (0.32) | — | |
| SCHEMBL20228237 | 0.79 | CYP11B1 (0.40) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | CTSS 3626/4885CTSK 3335/4885RARB 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.