SCHEMBL2494130

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7256852	0.85	ALDH1A1 (0.56)	EGFRPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL7256744	0.84	EGFR (0.70)	EGFRPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL2430311	0.77	ALDH1A1 (0.52)	EGFRNPC1RAB9AALDH1A1KDM4E
	SCHEMBL7257596	0.77	CDK4 (0.61)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL7262295	0.76	ALDH1A1 (0.57)	EGFRNPC1RAB9AALDH1A1KDM4E
	SCHEMBL28356517	0.75	EGFR (0.43)	EGFRPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL1136187	0.75	ALDH1A1 (0.42)	EGFRPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL7262267	0.74	ALDH1A1 (0.54)	NPC1RAB9AALDH1A1KDM4ECYP3A4
	SCHEMBL7256679	0.74	PLK4 (0.47)	EGFRIDO1NPC1RAB9AALDH1A1
	SCHEMBL1136181	0.74	IDO1 (0.40)	EGFRPRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.