Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24942954 | 0.93 | OPRM1 (0.34) | MAPK14OPRM1 | |
| SCHEMBL30112752 | 0.91 | NOTUM (0.32) | NOTUMHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL29250145 | 0.91 | NOTUM (0.32) | NOTUMHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL24942948 | 0.91 | OPRM1 (0.32) | OPRM1HPGDF10 | |
| SCHEMBL24942499 | 0.89 | OPRM1 (0.34) | NOTUMOPRM1HPGD | |
| SCHEMBL24942986 | 0.89 | OPRM1 (0.32) | OPRM1HPGD | |
| SCHEMBL24943033 | 0.88 | OPRM1 (0.32) | HTTOPRM1HPGD | |
| SCHEMBL18526237 | 0.88 | OPRM1 (0.35) | HTTMEN1ALDH1A1KMT2AOPRM1 | |
| SCHEMBL24942518 | 0.88 | OPRM1 (0.32) | OPRM1HPGD | |
| SCHEMBL24942966 | 0.87 | NT5E (0.39) | NOTUMHTTALDH1A1OPRM1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009503-A1 | 2-DIAZO-3-OXO-2,3-DIHYDROSPIRO[INDENE-1,9'-XANTHENE] DERIVATIVES AND SIMILAR COMPOUNDS AS PHOTOACTIVE FLUORESCENT COMPOUNDS FOR PROTEIN LABELING | EIKON THERAPEUTICS INC. (US) | 2023-02-02 | — | — | WO | disclosed |