Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24943342 | 1.00 | POLB (0.61) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL2220842 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL3739385 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL12435712 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL2214406 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL2220837 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL2214414 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL8510639 | 0.86 | POLB (0.54) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL12435714 | 0.86 | L3MBTL1 (0.54) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL12126804 | 0.86 | POLB (0.54) | POLBL3MBTL1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230304002-A1 | TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES | BANK OF AMERICA, N.A. | 2023-09-28 | — | — | US | disclosed |
| US-20230016929-A1 | EXTRAHEPATIC DELIVERY | BANK OF AMERICA, N.A. | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230304002-A1 | TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES | TTR, MTPN, CRYAA | POLB 150/4885L3MBTL1 3533/4885CHRM2 4874/4885 |
| US-20230016929-A1 | EXTRAHEPATIC DELIVERY | SLC10A1, FABP1, SLC67A1 | POLB 292/4885L3MBTL1 105/4885CHRM2 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.