SCHEMBL2494548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492760	0.85	CRHR1 (0.39)	ALDH1A1ALDH1A3ALDH3A1
	SCHEMBL136177	0.82	ALDH1A1 (0.41)	TSHRMAPTALDH1A1MEN1LMNA
	SCHEMBL29354732	0.82	KMT2A (0.50)	TSHRMAPTALDH1A1MEN1LMNA
	SCHEMBL465195	0.82	KMT2A (0.50)	TSHRMAPTALDH1A1MEN1LMNA
	SCHEMBL7665163	0.82	TSHR (0.36)	TSHRMAPTALDH1A1MEN1LMNA
	SCHEMBL31718395	0.82	TSHR (0.46)	TSHRMAPTALDH1A1MEN1LMNA
	SCHEMBL6299189	0.82	TSHR (0.46)	TSHRMAPTALDH1A1MEN1LMNA
	SCHEMBL2491664	0.81	TDP1 (0.37)	MAPTALDH1A1MEN1LMNAKMT2A
	SCHEMBL13778825	0.79	APP (0.43)	MAPTALDH1A1MEN1LMNAKMT2A
	SCHEMBL15387861	0.79	TSHR (0.34)	TSHRMAPTALDH1A1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.