Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945924 | 0.97 | MAPT (0.50) | MAPTFOLH1L3MBTL1SYKPOLB | |
| SCHEMBL4541834 | 0.88 | MAPT (0.56) | MAPTFOLH1TPSAB1TPSD1TPSG1 | |
| SCHEMBL1882392 | 0.88 | MAPT (0.56) | MAPTFOLH1TPSAB1TPSD1TPSG1 | |
| SCHEMBL24946310 | 0.82 | MEN1 (0.52) | MAPTSYKPOLBMAPK1MEN1 | |
| SCHEMBL24622413 | 0.82 | MAPT (0.60) | MAPTFOLH1L3MBTL1SYKPOLB | |
| SCHEMBL15723464 | 0.82 | MAPT (0.60) | MAPTFOLH1L3MBTL1SYKPOLB | |
| SCHEMBL15227896 | 0.81 | MAPT (0.50) | MAPTFOLH1TPSAB1TPSD1TPSG1 | |
| SCHEMBL18281086 | 0.81 | FOLH1 (0.52) | MAPTFOLH1L3MBTL1SYKPOLB | |
| SCHEMBL5490556 | 0.81 | MAPT (0.59) | MAPTL3MBTL1SYKPOLBMAPK1 | |
| SCHEMBL20168169 | 0.81 | MAPT (0.59) | MAPTL3MBTL1SYKPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |