Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945921 | 0.88 | MAPT (0.46) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL24945924 | 0.82 | MAPT (0.50) | MEN1KMT2AMAPTSYKMAPK1 | |
| SCHEMBL24945922 | 0.82 | MAPT (0.54) | MEN1KMT2AMAPTTDP1SYK | |
| SCHEMBL14485285 | 0.80 | SYK (0.62) | MEN1KMT2AMAPTTDP1NTSR1 | |
| SCHEMBL24946291 | 0.78 | L3MBTL1 (0.44) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL11973513 | 0.77 | ITGB3 (0.59) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL11973516 | 0.77 | ITGB3 (0.59) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL10589713 | 0.76 | NTSR1 (0.54) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL14485661 | 0.76 | CTSS (0.64) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL20136152 | 0.76 | CTSS (0.64) | MEN1KMT2AMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |