Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945922 | 0.97 | MAPT (0.54) | MAPTSYKL3MBTL1MEN1KMT2A | |
| SCHEMBL4541834 | 0.84 | MAPT (0.56) | MAPTFOLH1TPSAB1TPSD1TPSG1 | |
| SCHEMBL1882392 | 0.84 | MAPT (0.56) | MAPTFOLH1TPSAB1TPSD1TPSG1 | |
| SCHEMBL24946310 | 0.82 | MEN1 (0.52) | MAPTSYKMEN1KMT2APOLB | |
| SCHEMBL28151473 | 0.81 | MAPT (0.56) | MAPTSYKL3MBTL1MEN1KMT2A | |
| SCHEMBL15893683 | 0.81 | SYK (0.49) | MAPTSYKL3MBTL1MEN1KMT2A | |
| SCHEMBL21164376 | 0.80 | MAPT (0.55) | MAPTSYKL3MBTL1MEN1KMT2A | |
| SCHEMBL22433480 | 0.80 | SYK (0.48) | MAPTSYKL3MBTL1POLBMAPK1 | |
| SCHEMBL19868559 | 0.80 | L3MBTL1 (0.51) | MAPTSYKL3MBTL1MEN1KMT2A | |
| SCHEMBL19981176 | 0.80 | SYK (0.48) | MAPTSYKL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |