Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNA2 | P16389 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.37 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946157 | 0.79 | CTRC (0.37) | ALDH1A1KCNA2KCNA5KCNA1KCNA4 | |
| SCHEMBL24947194 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP3A4KCNA2KCNA5KCNA1 | |
| SCHEMBL25402611 | 0.78 | KDM4E (0.42) | ALDH1A1KCNA2KCNA5KCNA1KCNA4 | |
| SCHEMBL18602817 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP3A4 | |
| SCHEMBL25404609 | 0.77 | NOTUM (0.41) | ALDH1A1NOTUMCYP3A4GAAPTGS1 | |
| SCHEMBL24947190 | 0.76 | CAMK2A (0.39) | PTGS1 | |
| SCHEMBL24946159 | 0.75 | CYP1A2 (0.34) | — | |
| SCHEMBL24946532 | 0.74 | ALDH1A1 (0.40) | ALDH1A1CYP3A4KCNA2KCNA5KCNA1 | |
| SCHEMBL24947185 | 0.72 | HTR2C (0.30) | — | |
| SCHEMBL30911911 | 0.72 | KCNA3 (0.40) | KCNA2KCNA5KCNA1KCNA4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |