Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321884 | 1.00 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL1613087 | 0.89 | GPR119 (0.56) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL921685 | 0.87 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL30431475 | 0.87 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL24793975 | 0.87 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL24793973 | 0.87 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL29709671 | 0.87 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL25003975 | 0.86 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL22697070 | 0.86 | TERT (0.39) | GPR119KDM4EMAPTTHRBNAMPT | |
| SCHEMBL3436365 | 0.82 | GPR119 (0.58) | GPR119KDM4EMAPTTHRBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222631-A | Phenyl- [1,3] dioxolo [4,5-C ] pyridinyl-phenyl-, phenyl- [1,3] dioxolo [4,5-C ] pyridinyl-heteroaryl-or phenyl- [1,3] dioxolo [4,5-C ] pyridinyl-piperidinyl-methyl-oxetanylmethyl-1H-benzo [ D ] imidazole-carboxylic acid derivatives and methods of use thereof | 诚益生物(美国)公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |
| US-20220348564-A1 | PHENYL-[1,3]DIOXOLO[4,5-C]PYRIDINYL-PHENYL-, PHENYL-[1,3]DIOXOLO[4,5-C]PYRIDINYL-HETEROARYL-, OR PHENYL-(1,3)DIOXO[4,5-C]PYRIDINYL-PIPERIDINYL-METHYL-OXETANYLMETHYL-1H-BENZO[D]IMIDAZOLE-CARBOXYLIC ACID DERIVATIVES AND METHODS OF USING SAME | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2022-11-03 | — | — | US | disclosed |
| CN-113480534-B | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113480534-A | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药技术有限公司 | 2021-10-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348564-A1 | PHENYL-[1,3]DIOXOLO[4,5-C]PYRIDINYL-PHENYL-, PHENYL-[1,3]DIOXOLO[4,5-C]PYRIDINYL-HETEROARYL-, OR PHENYL-(1,3)DIOXO[4,5-C]PYRIDINYL-PIPERIDINYL-METHYL-OXETANYLMETHYL-1H-BENZO[D]IMIDAZOLE-CARBOXYLIC ACID DERIVATIVES AND METHODS OF USING SAME | GLP1R, GIPR, SLC5A1 | GPR119 6/4885KDM4E 2093/4885MAPT 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.